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Assisted Hatching’s Role In In-Vitro Fertilization

In order for an embryo to be implanted inside the uterus, it has to divide naturally so that a multi cell embryo that includes fluid cavity is created. That fluid cavity is known as blastocyst and is coated with Zona Pellucida, which is also known as Zona and is a gel like material. Blastocysts are implanted inside the uterus only when cells break through this Zona. This is the process that is referred to with the name hatching.

Should You Consider Assisted Hatching?

There are specific situations in which assisted hatching is recommended. Generally, people that see the following should consider it:

  • If the age of the woman is over 37.
  • If the woman’s Follicle Stimulating Hormone levels are elevated or if there is low AMH or Antral Follicle levels.
  • If the embryos are of a poor quality, with slower cell division rates or with excessive fragmentation presentation.
  • If the embryos have a really thick outer shell or Zona.
  • If there were failures that appeared with past IVF procedures.

IVF And Assisted Hatching

The truth is that it is really frustrating to go through an IVF cycle and see it fail. While you can easily go to some of the best clinics like CRGH London, there is no real 100% certainty that you will be successful during an IVF cycle.

Assisted hatching can be helpful as it will aid you to cope with various difficulties. That is because a defect is created in Zona, allowing a drastic increase in embryo hatching chances. Women find this particularly helpful, especially after going through many IVF cycles since thicker Zona shells will impair hatching and is a main cause of IVF failure.

The assisted hatched embryos will be implanted one day earlier. This allows a higher chance that the implant takes place. That is especially the case in the event that we have advanced endometrium because of ovarian stimulation. Such an extra laboratory manipulation does involve small damage risk during transfer and micromanipulation. Defect size is critical and can produce results that are undesired.

Success Rates With Assisted Hatching

Success rates are going to vary from one clinic to the next. This is due to the fact that the doctor that performs the procedure will have a huge impact on success rate. What is really important is that the embryologist is an expert. This will have the highest possible impact on the success rate.

We do have different actual live birth rates that appear from assisted hatching but as a general rule of thumb, you have higher chances of success when compared with other procedures as you are younger. This is because female fertility is going to diminish together with age. According to research, the procedure will not cause abnormality at a higher rate than with regular IVF procedures without assisted hatching.

On the whole, what has to be remembered about the success rates is that it counts what clinic you go to. Make sure that you research the actual success rates at the considered clinic before you make your final choice.


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